ملخصات الابحاث

المجالات البحثية

الابحاث العلمية

1 - Sulforaphane substantially impedes testicular ferroptosis in adult rats exposed to di-2-ethylhexyl phthalate through activation of NRF-2/SLC7A11/GPX-4 trajectory (2024).

2 - Sitagliptin alleviates renal steatosis and endoplasmic reticulum stress in high fat diet-induced obese rats by targeting SREBP-1/CD36 signaling pathway (2024).

3 - New therapeutic insight into the effect of bisphosphonates and phytoestrogens on mesenchymal stem cells therapy and bone structure in ovariectomized rats (2024).

4 - Effect of some natural products either alone or in combination form on gastritis induced in experimental animals (2024).

5 - Lipoprotein modulators relevant to certain cardiovascular risk factors in diabetes mellitus and hyperlipidaemia (2024).

6 - دور مثبطات تحلل السيترات على بعض مسارات الأيض فى الجرذان المستحدث فيها السكرى وارتفاع دهون الدم. Role of some ATP citrate lyase inhibitors on certain metabolic pathways in diabetic hyperlipidemic rats. (2024).

7 - Pentoxifylline as add-on treatment to donepezil in copper sulphate-induced Alzheimer’s disease-like neurodegeneration in rats (2023).

8 - Empaglifozin ameliorates liver fbrosis in NASH rat model via targeting hepatic NF‑κB/SOX9/OPN signaling and osteocalcin level (2023).

9 - Empagliflozin ameliorates liver fibrosis in NASH rat model via targeting hepatic NF‑κB/SOX9/OPN signaling and osteocalcin level (2023).

10 - Potential of Caffeic Acid and 10-Dehydrogingerdione as Lipid Regulators Relevant to Their Inhibitory Effect on miR-122 and ATP Citrate Lyase Activity in Diabetic Hyperlipidemic Rats (2023).

11 - Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats via the Akt/HIF-1α/VEGF signaling pathway (2023).

12 - Policosanol ameliorates renal inflammation and pyroptosis in hypercholesterolemic rabbits via modulation of HMGB1/PI3K/mTOR/NLRP3/Caspase-1 pathway (2022).

13 - Lycopene ameliorates hyperlipidemia via potentiation of AMP-activated protein kinase and inhibition of ATP-citrate lyase in diabetic hyperlipidemic rat model (2022).

14 - Residual Cardiovascular Risk, Attributed to Statins Escape Phenomenon and Policosanol Potential as Therapeutic Agent Mini Review Global Journal of Pharmacy & Pharmaceutical Sciences (2022).

15 - Ellagic acid ameliorates high fructose-induced hyperuricemia and non-alcoholic fatty liver in Wistar rats: Focusing on the role of C1q/tumor necrosis factor-related protein-3 and ATP citrate lyase (2022).

16 - 10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition (2022).

17 - Histopathological changes in submandibular gland and dorsal tongue of experimental rats due to prolonged tramadol intake focusing on novel modulatory effect of 10-dehydrogingerdione (2021).

18 - Wnt signaling pathway as a regulator of bone formation and healing. (2021).

19 - 10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats (2021).

20 - 10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats (2021).

21 - Effect of resveratrol and mesenchymal stem cell monotherapy and combined treatment in management of osteoporosis in ovariectomized rats: Role of SIRT1/FOXO3a and Wnt/β-catenin pathways (2021).

22 - 2. Modulation of NADPH oxidase and Nrf2/HO‐1 pathway by vanillin in cisplatin‐induced nephrotoxicity in rats (2020).

23 - Losartan and azelastine either alone or in combination as modulators for endothelial dysfunction and platelets activation in diabetic hyperlipidemic rats (2020).

24 - Early myocardial injury biomarkers in diabetic hyperlipidemic rats: Impact of 10-dehydrogingerdione and vitamin D3 (2020).

25 - Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model (2020).

26 - Vitamin D3 intake as modulator for the early biomarkers of myocardial tissue injury in diabetic hyperlipidaemic rats. (2020).

27 - Vitamin D3 intake as modulator for the early biomarkers of myocardial tissue injury in diabetic hyperlipidaemic rats (2020).

28 - Dyslipidemia induced inflammatory status, platelet activation and endothelial dysfunction in rabbits: Protective role of 10-Dehydrogingerdione. (2019).

29 - The modulation of PCSK-9 and GAGs by 10-dehydrogingerdione and pentoxifylline in hyperlipidemic rabbits. (2018).

30 - Inhibition of Aortic Calcification by Policosanol in Dyslipidemic Rabbits Is Enhanced by Pentoxifylline: Potential Role of PCSK9. (2018).

31 - Potential therapeutic roles of 10-dehydrogingerdione and/or pentoxifylline against calcium deposition in aortic tissues of high dietary cholesterol-fed rabbits. (2018).

32 - Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats. (2018).

33 - New Insight on a Combination of Policosanol and 10-Dehydrogingerdione Phytochemicals as Inhibitors for Platelet Activation Biomarkers and Atherogenicity Risk in Dyslipidemic Rabbits: Role of CETP and PCSK9 Inhibition (2018).

34 - Nephrotoxicity Induced by Cisplatin Intake in Experimental Rats and Therapeutic Approach of Using Mesenchymal Stem Cells and Spironolactone (2018).

35 - Effect of zinc gluconate, sage oil on inflammatory patterns and hyperglycemia in zinc deficient diabetic rats (2017).

36 - Omega 3 fatty acids intake versus diclofenac in osteoarthritis induced in experimental rats (2017).

37 - Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylation in diabetic rats (2017).

38 - Peptide Hydroxamate derivatives as regulator for insulin receptor signaling and its degradation by Zn metalloproteinase in Diabetic rats (2016).

39 - The synergistic effect between vanillin and doxorubicin in ehrlich ascites carcinoma solid tumor and MCF-7 human breast cancer cell line (2016).

40 - w-3 fatty acids , atorvastatin as modulator for inflammatory pattern versus Diclofenac in osteoartheritis induced in Experimental rats (2016).

41 - 10DHGD ameliorates cisplatin-induced nephrotoxicity in rats (2016).

42 - Policosanol as a new inhibitor candidate for vascular calcification in diabetic hyperlipidemic rats. (2016).

43 - Atheroprotective potentials of curcuminoids against ginger extract in hypercholesterolaemic rabbits (2015).

44 - Haemostatic risk factors in dyslipidemic rabbits: role of 10-dehydrogingerdione as a new hypolipemic agent (2015).

45 - Renal injury induced in alloxan diabetic rats. Role of Mycophenolate Mofetil as therapeutic agent. (2014).

46 - Pyridoxamine, an inhibitor of protein glycation, in relation to microalbuminuria and proinflammatory cytokines in experimental diabetic nephropathy. (2014).

47 - Chronic effects of clozapine administration on insulin resistance in rats: evidence for adverse metabolic effects. (2014).

48 - Diabetic Renal Injury Induced in Experimental Rats-Role of Curcuminoids as Probable Therapeutic Agent (2013).

49 - 10-Dehydrogingerdione raises HDL-cholesterol through a CETP inhibition and wards off oxidation and inflammation in dyslipidemic rabbits (2013).

50 - Pattern of fatty acids as modulator for dietary iron overload and its influences on testicular function of experime (2013).

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